US update: 16 Americans at Nebraska Biocontainment Unit (1 confirmed, 15 monitoring); 2 at Emory University Hospital Atlanta — 1 symptomatic with PCR result pending. Tristan da Cunha community PCR screening results from GeneXpert rig still pending.
ECDC updates official count to 11 (9 lab-confirmed + 2 probable), 3 deaths. MV Hondius departs Tenerife for Rotterdam for crew offload and ship-wide hantavirus decontamination (4–6 weeks). WHO Director-General: 'There is no sign that we're seeing the start of a larger outbreak.'
WHO Director-General Tedros Adhanom Ghebreyesus, briefing reporters in Tenerife, said: "This is not another COVID. The risk to the public is low." Tedros reiterated that human-to-human Andes virus transmission is limited to close-contact settings and that the multi-country evacuation should not change the overall WHO public-risk assessment, which remains very low.
CDC activates Level 3 emergency response for the MV Hondius outbreak — the agency's mid-tier activation that mobilises an Emergency Operations Center team and deploys epidemiologists and medical staff to the affected region. The CDC team is conducting per-passenger exposure risk assessments for the 18 repatriated US nationals and is coordinating with HHS on the Nebraska Biocontainment Unit transfer.
France confirms second case: a French woman evacuated from MV Hondius tests PCR-positive — the second of 5 repatriated French nationals to test positive. France total: 2 cases. HantaCount headline updates to 16 cases, CFR 19%.
Spain confirms second case: a Spanish male passenger in Madrid hospital tested PCR-positive on arrival screening; asymptomatic and in good health. This is distinct from the May 8 Alicante case (South African woman). Spain total: 2 cases.
Radboud UMC (Nijmegen, Netherlands): 12 hospital staff placed in 6-week preventive quarantine after protocol breaches in handling an MV Hondius patient. Blood samples were processed under standard rather than ANDV-strict protocol; urine disposal did not follow latest international guidelines. Hospital states the probability of actual infection is very small.
First US case confirmed: HHS announced one of the 18 repatriated American passengers tested PCR-positive for Andes hantavirus on the trans-Atlantic flight (asymptomatic at testing). Patient transported in a biocontainment unit to the Nebraska Biocontainment Unit at University of Nebraska Medical Center for follow-up. A second American with mild symptoms is being routed to a separate ASPR RESPTC. HantaCount headline updates to 14 cases (13 + 1 US PCR-positive), CFR 21%.
Methodology lock-in: HantaCount headline aligned to the sum of national health agency reports (NL 2 + ZA 1 + GB 3 + CH 1 + ES 1 + DE 1 + FR 1 + TR 1 + CV 1 + SH 1 = 13 cases, 3 deaths, CFR 23%). Each country count now carries an explicit source. WHO DON-600 baseline (8 cases, 6 lab-confirmed + 2 probable, CFR 38%) shown separately for direct comparison.
Updated disembarkation count: 94 of the 147 onboard passengers disembarked on the first day (10 May), representing 19 different nationalities. Beyond the 13 countries with cases, additional passenger nationalities include Australia, Belgium, Greece, Guatemala, India, Japan, Montenegro, New Zealand, Poland, Portugal, Russia and Ukraine — these countries are conducting precautionary contact monitoring even though no cases have been confirmed among their nationals.
WHO coordinates shipment of 2,500 Andes virus diagnostic kits from Instituto Malbrán (Argentina) to reference laboratories in Spain, France, Netherlands, United Kingdom and South Africa. Tristan da Cunha team installs Cepheid GeneXpert PCR rig at Camogli Hospital — first community screening results expected within 48 hours.
Tenerife disembarkation operation completes. UK Health Security Agency confirms a third British national positive for Andes virus on the repatriation flight. One French passenger develops symptoms in-flight to Paris and is isolated on arrival at Bichat. WHO updated Tristan da Cunha case timeline: probable case is an adult male resident who disembarked at Saint Helena on 14 April, symptom onset 28 April (diarrhoea, then fever); currently stable in isolation. One previously suspected case has been reclassified as non-case after PCR and serology negative.
WHO confirms 46 passengers disembarked at Tenerife in the first wave; first Spanish charter (14 passengers) reached Madrid. France evacuates 5 nationals to Paris under 72-hour hospital observation + 45-day home quarantine protocol. UK military paratroopers airdrop medical clinicians and equipment to Tristan da Cunha. After full disembarkation MV Hondius will continue to Rotterdam for crew offload and ship-wide disinfection.
Spanish health authorities confirm disembarkation order: Spanish nationals first, flown to Madrid Gomez-Ulla military hospital for quarantine; followed by Netherlands, Canada, Türkiye, France, United Kingdom, Ireland and United States. Spain's health minister states remaining passengers are asymptomatic.
Passenger disembarkation begins at Tenerife under strict medical supervision. UK Health Security Agency confirms second British case.
Spanische Gesundheitsbehörden bestätigen die Ausschiffungsreihenfolge: zuerst spanische Staatsangehörige, geflogen zur Quarantäne ins Militärkrankenhaus Gómez Ulla in Madrid; gefolgt von Niederlanden, Kanada, Türkiye, Frankreich, Vereinigtem Königreich, Irland und USA. Die spanische Gesundheitsministerin erklärt, dass die verbleibenden Passagiere asymptomatisch sind.
Passagierausschiffung beginnt in Teneriffa unter medizinischer Aufsicht; UK Health Security Agency bestätigt zweiten britischen Fall.
Regierung von Tristan da Cunha meldet Verdachtsfall von Hantavirus bei einem Einwohner, der am 24. April von Bord gegangen ist. Ein Besatzungsmitglied, das den Hondius per Flugzeug verlassen hat, wurde negativ getestet.
WHO veröffentlicht DON-600: 8 Fälle (6 bestätigt, 2 wahrscheinlich), 3 Todesfälle, CFR 38 %. Schiff in Teneriffa angedockt; Passagierausschiffung für 10. Mai geplant. 17 Amerikaner zur Offutt AFB repatriiert; keine Pflichtquarantäne.
MV Hondius kommt in Teneriffa (Hafen Granadilla de Abona) an; WHO-Generaldirektor reist auf die Kanarischen Inseln, um die Ausschiffung der 147 an Bord zu koordinieren. Frankreich und Singapur zum Kontaktverfolgungsnetzwerk hinzugefügt; 7 US-Bundesstaaten überwachen Passagiere.
CDC kündigt Rückholflug an; Spanien bestätigt Fall in Alicante; USA überwacht in 5 Bundesstaaten.
Schweiz bestätigt ersten europäischen Fall; 40 Passagiere evakuiert.
Argentinien eröffnet Untersuchung zur Expositionsquelle vor der Kreuzfahrt.
WHO veröffentlicht Krankheitsausbruchsmeldung (DON-599) — Andes-Virus bestätigt.
Zwei Todesfälle an Bord; PCR-Proben nach Lissabon geschickt.
Erste Passagiere berichten über grippeähnliche Symptome.
Mehrere Dutzend Passagiere gehen in St. Helena von Bord; später für die Kontaktverfolgung identifiziert.
Die MV Hondius verlässt Argentinien mit mehr als 240 Passagieren.