US update: 16 Americans at Nebraska Biocontainment Unit (1 confirmed, 15 monitoring); 2 at Emory University Hospital Atlanta — 1 symptomatic with PCR result pending. Tristan da Cunha community PCR screening results from GeneXpert rig still pending.
ECDC updates official count to 11 (9 lab-confirmed + 2 probable), 3 deaths. MV Hondius departs Tenerife for Rotterdam for crew offload and ship-wide hantavirus decontamination (4–6 weeks). WHO Director-General: 'There is no sign that we're seeing the start of a larger outbreak.'
WHO Director-General Tedros Adhanom Ghebreyesus, briefing reporters in Tenerife, said: "This is not another COVID. The risk to the public is low." Tedros reiterated that human-to-human Andes virus transmission is limited to close-contact settings and that the multi-country evacuation should not change the overall WHO public-risk assessment, which remains very low.
CDC activates Level 3 emergency response for the MV Hondius outbreak — the agency's mid-tier activation that mobilises an Emergency Operations Center team and deploys epidemiologists and medical staff to the affected region. The CDC team is conducting per-passenger exposure risk assessments for the 18 repatriated US nationals and is coordinating with HHS on the Nebraska Biocontainment Unit transfer.
France confirms second case: a French woman evacuated from MV Hondius tests PCR-positive — the second of 5 repatriated French nationals to test positive. France total: 2 cases. HantaCount headline updates to 16 cases, CFR 19%.
Spain confirms second case: a Spanish male passenger in Madrid hospital tested PCR-positive on arrival screening; asymptomatic and in good health. This is distinct from the May 8 Alicante case (South African woman). Spain total: 2 cases.
Radboud UMC (Nijmegen, Netherlands): 12 hospital staff placed in 6-week preventive quarantine after protocol breaches in handling an MV Hondius patient. Blood samples were processed under standard rather than ANDV-strict protocol; urine disposal did not follow latest international guidelines. Hospital states the probability of actual infection is very small.
First US case confirmed: HHS announced one of the 18 repatriated American passengers tested PCR-positive for Andes hantavirus on the trans-Atlantic flight (asymptomatic at testing). Patient transported in a biocontainment unit to the Nebraska Biocontainment Unit at University of Nebraska Medical Center for follow-up. A second American with mild symptoms is being routed to a separate ASPR RESPTC. HantaCount headline updates to 14 cases (13 + 1 US PCR-positive), CFR 21%.
Methodology lock-in: HantaCount headline aligned to the sum of national health agency reports (NL 2 + ZA 1 + GB 3 + CH 1 + ES 1 + DE 1 + FR 1 + TR 1 + CV 1 + SH 1 = 13 cases, 3 deaths, CFR 23%). Each country count now carries an explicit source. WHO DON-600 baseline (8 cases, 6 lab-confirmed + 2 probable, CFR 38%) shown separately for direct comparison.
Updated disembarkation count: 94 of the 147 onboard passengers disembarked on the first day (10 May), representing 19 different nationalities. Beyond the 13 countries with cases, additional passenger nationalities include Australia, Belgium, Greece, Guatemala, India, Japan, Montenegro, New Zealand, Poland, Portugal, Russia and Ukraine — these countries are conducting precautionary contact monitoring even though no cases have been confirmed among their nationals.
WHO coordinates shipment of 2,500 Andes virus diagnostic kits from Instituto Malbrán (Argentina) to reference laboratories in Spain, France, Netherlands, United Kingdom and South Africa. Tristan da Cunha team installs Cepheid GeneXpert PCR rig at Camogli Hospital — first community screening results expected within 48 hours.
Tenerife disembarkation operation completes. UK Health Security Agency confirms a third British national positive for Andes virus on the repatriation flight. One French passenger develops symptoms in-flight to Paris and is isolated on arrival at Bichat. WHO updated Tristan da Cunha case timeline: probable case is an adult male resident who disembarked at Saint Helena on 14 April, symptom onset 28 April (diarrhoea, then fever); currently stable in isolation. One previously suspected case has been reclassified as non-case after PCR and serology negative.
WHO confirms 46 passengers disembarked at Tenerife in the first wave; first Spanish charter (14 passengers) reached Madrid. France evacuates 5 nationals to Paris under 72-hour hospital observation + 45-day home quarantine protocol. UK military paratroopers airdrop medical clinicians and equipment to Tristan da Cunha. After full disembarkation MV Hondius will continue to Rotterdam for crew offload and ship-wide disinfection.
Spanish health authorities confirm disembarkation order: Spanish nationals first, flown to Madrid Gomez-Ulla military hospital for quarantine; followed by Netherlands, Canada, Türkiye, France, United Kingdom, Ireland and United States. Spain's health minister states remaining passengers are asymptomatic.
Passenger disembarkation begins at Tenerife under strict medical supervision. UK Health Security Agency confirms second British case.
スペイン保健当局が下船順序を確認：スペイン人を最優先とし、検疫のためマドリードのゴメスウジャ陸軍病院へ空輸。続いてオランダ、カナダ、トルコ、フランス、英国、アイルランド、米国。スペイン保健相は残乗客が無症状と発表。
テネリフェで医療監視のもと乗客の下船が開始。英国健康安全保障庁が2番目の英国症例を確認。
トリスタンダクーニャ政府が4月24日に下船した住民のハンタウイルス疑い症例を報告。ホンディウスを航空機で離れた乗組員が陰性と判明。
WHOがDON-600を発行：8症例（確認6件・疑い2件）、3名死亡、致命率38%。船がテネリフェに入港。5月10日に乗客の下船を計画。米国人17名がオファット空軍基地に帰国予定。強制隔離なし。
MVホンディウスがテネリフェ（グラナディジャ・デ・アボナ港）に到着。WHO事務局長が船内147名の下船調整のためカナリア諸島へ。フランスとシンガポールが接触者追跡ネットワークに追加。7つの米国州が乗客を監視中。
CDCが帰国便を発表。スペインがアリカンテで症例を確認。米国が5州で監視を実施。
スイスが最初の欧州症例を確認。40名の乗客が避難。
アルゼンチンがクルーズ前の曝露源についての調査を開始。
WHOが疾病発生報告（DON-599）を発行 — アンデスウイルス確認。
船内で2名死亡。PCR検体がリスボンに送られる。
最初の乗客がインフルエンザ様症状を報告。
数十名の乗客がセントヘレナで下船。後に接触者追跡のため特定される。
MVホンディウスが240名以上の乗客を乗せてアルゼンチンを出港。